Veterinary drug AmoxyBAG LC

For use in clinical cases of bovine mastitis during lactation period

  • Broad spectrum of antibacterial activity

  • Synergistic effect of active substances

  • Anti-inflammatory and anti-allergic effect


Therapeutic indications:

AmoxyBAG LC is indicated for treatment of clinical mastitis in lactating cows caused by pathogens sensitive to amoxicillin and clavulanic acid.

Composition of the veterinary drug:

One AmoxyBAG LC intramammary syringe of 3 g contains:

  • Amoxicillin trihydrate equivalent to amoxicillin 200 mg
  • Potassium clavulanate equivalent to clavulanic acid 55 mg
  • Prednisolone 10 mg

Pharmacological activity:

The veterinary drug is a combination of amoxicillin, clavulanic acid and prednisolone. Active substances of the veterinary drug have synergistic effect, enhancing each other’s activity and expanding the spectrum of antimicrobial activity against bovine mastitis pathogens.

Amoxicillin is a semi-synthetic antibiotic from the group of penicillins (4-hydroxy analog of ampicillin) with a broad spectrum of activity. Biological activity is manifested by inhibition of transpeptidase, an enzyme involved in the synthesis of cell walls.

Clavulanic acid irreversibly inhibits ß-lactamases, thereby protecting amoxicillin from destruction and increasing its activity.

Prednisolone has anti-inflammatory and anti-allergic activities, reduces swelling and inflammation of the bovine mammary gland affected by mastitis. Prednisolone does not inhibit leukocyte activity, and increases antibiotic penetration into tissues.

AmoxyBAG LC has a broad spectrum of bactericidal activity against most gram-positive and gram-negative bacteria, including ß-lactamase-producing strains (Streptococcus spp., Staphylococcus spp., Corynebacterium spp., Clostridium spp., Actinomyces bovis, Escherichia coli, Salmonella spp., Campylobacter spp., Klebsiella spp., Proteus spp., Pasteurella spp., Haemophilus spp., Actinobacillus spp., etc).


The veterinary drug should be infused into each affected quarter via the teat canal, immediately after milking, at 12 hour intervals for three consecutive milkings, in a dose of 3.0 g (one syringe).

Before the drug administration, milk out the treated udder quarters; clean and disinfect the nipples. Carefully put the tip of the syringe in the nipple canal and squeeze out the syringe content. The contents of one syringe is squeezed out in every quarter of the udder. After the drug administration, remove the syringe, pinch the end of the nipple and massage the nipple upwards during 1-2 minutes for better drug distribution.

Before use, warm the drug up to the body temperature of the animal.

Precautions and adverse reactions:

Do not use in animals with hypersensitivity to the components of the drug.

Use of this drug with other drugs is allowed, with the exception of drugs for intracisternal administration.

Overdose symptoms have not been revealed.

When the drug is used in recommended doses and in accordance with all the instructions, side effects and complications are generally not observed. In case of an allergic reaction, the drug should be cancelled; antihistamines, calcium should be prescribed.

The peculiarities of the action of the drug during its first use and cancellation are not identified. If dose is missed, resume the drug use in the same dosage and according to the same treatment regimen.

Withdrawal period:

Animals must not be slaughtered for human consumption within 7 days after the last treatment. Meat of animals forcibly slaughtered earlier than the specified period may be used for feeding carnivores. Milk for human consumption may only be taken after 72 hours from the last treatment. During the period of treatment and until the end of the specified period milk should be used as animal feed.

Storage conditions:

Store in a dry, dark place at a temperature of +2C to +25C.


Shelf-life of the veterinary drug under appropriate storage conditions is18 months from the date of manufacture.

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