Vermectin

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Veterinary drug Vermectin


For prevention and treatment of infectious diseases caused by parasitic nematodes and arthropods



  • Broad spectrum of antiparasitic activity

  • Effective against internal and external parasites

  • Quick absorption

  • Antiparasitic activity lasts for at least 10 days

  • Single administration


Therapeutic indications:

Veterinary drug Vermectin is indicated for cattle, sheep, goats, horses and pigs for prevention and treatment of parasitic diseases of gastrointestinal tract and lungs, caused by parasitic nematodes and arthropods.

  • For cattle, sheep and goats for prevention and treatment of parasitic diseases, caused by Ostertagia spp., Haemonchus spp., Trichostrongylus spp., Cooperia spp., Nematodirus spp., Bunostomum spp., Strongyloides spp., Oesophagostomum spp., Trichuris (Trichocephalus) spp., Dictyocaulus spp., Thelazia spp., Hypoderma, Oedemagena, Psoroptes, Sarcoptes, Oestrus, Linognathus, Haematopinus, Solenopotes, and against ixodid ticks.
  • For pigs for prevention and treatment of parasitic diseases, caused by Ascaris suum, Strongyloides spp., Oesophagostomum spp., Trichuris (Trichocephalus) spp., Metastrongylus spp., Sarcoptes and Haematopinus.
  • For horses for prevention and treatment of parasitic diseases, caused by Раrаscaris equorum, Strongyloides spp., Delafondia vulgaris, Alfortia edentates, Strongylus equinus, Oxyuris equi, Thelazia spp., Оnchocerca spp., Rhinoestrus spp.,  Gastrophilus spp., Psoroptes, Sarcoptes and against ixodid ticks.

Composition of the veterinary drug:

1 ml Vermectin solution for injection contains:

  • Ivermectin 10 mg as an active substance;

Pharmacological activity:

Vermectin is an antiparasitic veterinary drug. The active substance of the drug is ivermectin with a broad spectrum of antiparasitic activity against larval and matured nematodes: Oesophagostomum spp., Ostertagia spp.( including encapsulated larvae), Haemonchus spp., Trichostrongylus spp., Cooperia spp., Bunostomum spp., Strongyloides spp., Dictyocaulus spp., Thelazia spp., Nematodirus spp., Trichuris (Trichocephalus) spp., Metastrongylus spp., Parafilaria bovicola, Ascaris suum etc.; larvae of subcutaneous and nasopharyngeal gadfly, such as Hypoderma и Oestrus; biting louse and lice, such as Bovicola, Haematopinus, Linognathus, Solenopotes; scabies mites, such as Psoroptes и Sarcoptes; ixodid ticks (Rhipicephalus microplus) etc.

Ivermectin binds to cell receptors of muscle and nerve tissue of parasites and increases the permeability of membranes for chloride ions, which leads to blockade of the electrical activity of nerve and muscle cells of nematodes and arthropods, their paralysis and death.

After administration of the veterinary drug ivermectin is rapidly absorbed from the injection site and penetrates into organs and tissues of the animal, which protects animals from reinfection for 10-14 days after treatment, and from reinfection with Dictyocaulus viviparus for up to 21 days. Ivermectin is excreted mainly with bile and urine; a small amount is excreted with milk in lactating animals.

In recommended doses, Vermectin does not have a mutagenic, teratogenic and embryotoxic effects. The veterinary drug is toxic to fish and bees.

Dosage:

The veterinary drug is administered in the following doses:

  • Cattle, sheep, goats and horses – single doses of 1 ml /50 kg body weight, by intramuscular or subcutaneous injection; in case of infectious disease, caused by Psoroptes – double doses of 1 ml /50 kg body weight, at 7-10 days interval.
  • Pigs – single doses of 1 ml /33 kg body weight, by intramuscular injection; in case of infectious disease, caused by Sarcoptes – double doses of 1 ml /33 kg body weight, at 10-14 days interval.

Vermectin should be injected slowly, before use heat the injection solution up to the body temperature of the animal.

Precautions and adverse reactions:

Agitation, sialorrhea, increased bowel movements and urination, ataxia can occur in case of animal’s hypersensitivity. These symptoms usually disappear without use of therapeutic agents.

Do not use in animals less than two weeks before calving and within two weeks after calving, and also in thin, sick and lactating animals.

Do not use simultaneously with veterinary drugs, that contain macrocyclic lactones.

Withdrawal period:

Animals must not be slaughtered for human consumption within 28 days after the last treatment. Meat of animals forcibly slaughtered earlier than the specified period may be used for feeding carnivores.

Do not use the veterinary drug in animals whose milk is used for human consumption.

Storage conditions:

Store in a dry, dark place at a temperature of +2C to +25C. Keep out of reach of children.

Shelf-life:

Shelf-life of the veterinary drug under appropriate storage conditions is 3 years from the date of manufacture. Shelf-life after first opening: 28 days. Unused veterinary drug is utilized in accordance with the requirements of the law.

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