Dectomectin

Veterinary drug DECTOMECTIN


For prevention and treatment of parasitic diseases caused by nematodes and arthropods



  • Broad spectrum of antiparasitic activity

  • Effective against internal and external parasites

  • Long-lasting antiparasitic effect and protection against reinfection (for 28 days)

  • Easy resorption from the injection site


Therapeutic indications:

Veterinary drug DECTOMECTIN is indicated for cattle, sheep and pigs for prevention and treatment of parasitic diseases, caused by nematodes of gastrointestinal tract, lungs, subcutaneous tissue, lacrimal ducts; by larvae of subcutaneous and nasopharyngeal gadfly, larvae of flies, lice, scabies mites and ixodid ticks, which are sensitive to doramectin.

Composition of the veterinary drug:

1 ml DECTOMECTIN solution for injection contains:

  • Doramectin 10 mg as an active substance;

Pharmacological activity:

The active substance of the veterinary drug is doramectin with a broad spectrum of antiparasitic activity against nematodes: Oesophagostomum spp., Ostertagia spp. (including encapsulated larvae), Haemonchus spp., Trichostrongylus spp., Cooperia spp., Bunostomum spp., Strongyloides spp., Dictyocaulus spp., Thelazia spp., Nematodirus spp., Trichuris (Trichocephalus) spp., Metastrongylus spp., Parafilaria bovicola, Ascaris suum etc.; larvae of subcutaneous and nasopharyngeal gadfly, such as Hypoderma and Oestrus; biting louse and lice, such as Bovicola, Haematopinus, Linognathus, Solenopotes; scabies mites, such as Psoroptes и Sarcoptes; ixodid ticks (Rhipicephalus microplus) etc.

Doramectin is a macrocyclic lactone. It binds to cell receptors of muscle and nerve tissue of parasites and increases the permeability of membranes for chloride ions, which leads to blockade of the electrical activity in the nerve and muscle cells of nematodes and arthropods, and consequently paralysis and death.

The veterinary drug is easily resorbed from the injection site. Pharmacokinetics of doramectin provides long-term maintenance of therapeutic concentrations of the veterinary drug in blood of animals and protect them from parasitic diseases and reinfection for a long time (up to 28 days).

In recommended doses, Dectomectin does not have a mutagenic, teratogenic and embryotoxic effects. The veterinary drug has a low toxicity for warm-blooded animals.

Dosage:

The veterinary drug is administered in the following doses:

  • Cattle and sheep – single dose of 1 ml per 50 kg body weight, by intramuscular (in the middle third of the neck) or subcutaneous (in the neck or shoulder area) injection.
  • Pigs – single dose of 1 ml per 33 kg body weight, by intramuscular injection (in the base of the ear).

Heat the injection solution up to the body temperature of the animal before use. Inject slowly.

Precautions and adverse reactions:

Before mass treatment of animals, each batch of the drug is checked on a small group of animals (7-10 heads) of different ages and fatness. In the absence of signs of side, within three days after the administration of the drug, use the drug to treat the entire livestock.

In recommended doses, the veterinary drug doesn’t usually cause side effects and complications. In case of occurrence of allergic reactions DECTOMECTIN is cancelled, antihistamines and symptomatic treatment are prescribed.

In case of the overdose of the veterinary drug, weakness, tremor and increased salivation may occur. There are no specific detoxification agents; general measures should be taken to remove the veterinary drug from the animal’s body.

Do not use in animals which are known to be hypersensitive to substances of the veterinary drug.

Do not use in cows and sheep less than two weeks before calving and during the lactation period as well as in emaciated animals and animals with acute infectious diseases.

Do not use simultaneously with veterinary drugs, that contain macrocyclic lactones, this may result in increased toxicity of the veterinary drug.

Withdrawal period:

Cattle and sheep must not be slaughtered for human consumption within 70 days after the last treatment, pigs – 77 days after the last treatment. Meat of animals forcibly slaughtered earlier than the specified period may be used for feeding carnivores; internal organs of slaughtered animals must be disposed.

Do not use the veterinary drug in animals whose milk is used for human consumption.

Storage conditions:

Store in a dry, dark place at a temperature of +15C to +25C. Keep out of reach of children.

Shelf-life:

Shelf-life of the veterinary drug under appropriate storage conditions is 3 years from the date of manufacture. Shelf-life after first opening: 6 months. Don’t use after expiration date. Unused veterinary drug is utilized in accordance with the requirements of the law.

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