Enmitryl 50

Veterinary drug ENMITRYL 50


For the treatment of a wide range of infectious diseases in farm animals



  • Broad spectrum of activity

  • Effective in the treatment of multi-infections

  • High stability and bioavailability

  • Optimal dosage for small and medium-sized ungulates

Therapeutic indications:

Veterinary drug ENMITRYL 50 is used for treatment of calves, pigs, goats and sheep with respiratory infections, infections of gastrointestinal tract, genitourinary system, septicemia, colibacillosis, salmonellosis, streptococcosis, bacterial and enzootic pneumonia, atrophic rhinitis, mastitis-metritis-agalactia syndrome, multi-infections, bacterial complications in viral diseases and other diseases, the causative agents of which are sensitive to enrofloxacin.

Composition of the veterinary drug:

1 ml of ENMITRYL 50 contains 50 mg of enrofloxacin as an active substance.

Pharmacological activity:

The active substance of the veterinary drug is enrofloxacin, which is an antibiotic from the group of fluoroquinolones with a broad spectrum of bactericidal and antimycoplasmic activity.

Enrofloxacin is active against gram-positive and gram-negative microorganisms, such as Escherichia coli, Salmonella spp., Pasteurella multocida, Mannheimia haemolytica, Staphylococcus aureus, Staphylococcus hyicus, Streptococcus spp., Klebsiella spp., Pseudomonas aeruginosa, Bordetella bronchiseptica, Campylobacter spp., Corynebacterium pyogenes, Proteus spp., Mycoplasma spp., Brucella canis, Actinobacillus spp., Listeria monocytogenes, Haemophilus spp., Clostridium perfringens and others.

The mechanism of action of enrofloxacin is to inhibit the activity of the enzyme gyrase, which affects the replication of the DNA helix of the bacterial cell.

When administered parenterally, enrofloxacin is rapidly absorbed from the injection site and penetrates into most organs and tissues of the body. The maximum concentration of enrofloxacin in the blood is reached after 4–6 hours, the therapeutic concentration is maintained for 24 hours after administration. Enrofloxacin is excreted from the body mainly unchanged and partly in the form of a metabolite - ciprofloxacin, mainly in urine and bile.

Dosage:

The drug is used once a day:

- calves at a dose of 5 mg of enrofloxacin per 1 kg of animal body weight, which corresponds to 1 ml of the drug per 10 kg of animal body weight, subcutaneously for 3-5 days.

- pigs at a dose of 2.5 mg of enrofloxacin per 1 kg of animal body weight, which corresponds to 0.5 ml of the drug per 10 kg of animal body weight, intramuscularly for 3 days. For gastrointestinal tract infections or septicemia caused by Escherichia coli, the drug is prescribed at a dose of 5 mg of enrofloxacin per 1 kg of animal body weight, which corresponds to 1 ml of the drug per 10 kg of animal body weight, for 3 days subcutaneously.

- goats and sheep at a dose of 5 mg of enrofloxacin per 1 kg of animal body weight, which corresponds to 1 ml of the drug per 10 kg of animal body weight, for 3 days subcutaneously.

Due to a possible painful reaction, the drug should not be injected in one site: calves in a volume of more than 10 ml, pigs in a volume of more than 3 ml, goats and sheep in a volume of more than 6 ml.

Precautions and adverse reactions:

When using the drug in accordance with this instruction, side effects and complications generally are not observed. In some animals, after using the drug, a temporary dysfunction of the gastrointestinal tract (vomiting, diarrhea) is possible. When allergic reactions (itching, swelling) occurs, the drug is cancelled and the calcium preparations or antihistamines are prescribed.

In case of an overdose of the drug, the animal may experience a decrease in appetite, depression, vomiting, diarrhea. There is no specific antidote. In case of an overdose, use symptomatic treatment.

Contraindication to the use of the drug is the increased individual sensitivity of the animal to fluoroquinolones. Do not use the drug in case of heavy cartilage-related diseases; lesions of the nervous system, accompanied by convulsions; and also in the presence fluoroquinolone-resistant microorganisms.

Avoid missing the next dose of the drug, it can lead to a decrease in the therapeutic efficacy of the drug. If dose is missed, resume the drug use in the same dosage and according to the same treatment regimen.

After the first administration and cancellation no peculiarities are revealed.

When administered to lactating and pregnant animals, no peculiarities are revealed.

Do not use simultaneously with antibiotics from groups of phenicols, macrolides, tetracyclines, theophylline and non-steroidal anti-inflammatory drugs.

 

Withdrawal period:

Slaughter of animals for meat is allowed no earlier than 14 days after the last treatment. Meat of animals forcibly slaughtered earlier than the specified period may be used for feeding carnivores. Milk for human consumption may only be taken after 7 days from the last treatment.

Storage conditions:

Store in a dry, protected from light place at a temperature of +2 C0 to +25 C0.

Shelf-life:

Shelf life of the veterinary drug is 3 years from the date of production, after first opening of the bottle - 28 days.

Available without prescribtion.

Создание сайтов в Минске - Aliva.by